Pituitary “incidentaloma”: Neuroradiological assessment and differential diagnosis
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MANAGEMENT OF ENDOCRINE DISEASE: Pituitary 'incidentaloma': neuroradiological assessment and differential diagnosis.
Pituitary incidentalomas are a by-product of modern imaging technology. The term 'incidentaloma' is neither a distinct diagnosis nor a pathological entity. Rather, it is a collective designation for different entities that are discovered fortuitously, requiring a working diagnosis based on the input of the radiologist, endocrinologist and often a neurosurgeon. In addition to pathological condit...
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INTRODUCTION Carney complex is an autosomal dominant syndrome with multiple neoplasms in different sites, including myxomas, endocrine tumors and lentigines lesions. To the best of our knowledge, this is the first report of Carney complex presenting with a unilateral adrenal adenoma associated with a pituitary incidentaloma. CASE PRESENTATION A 27-year-old Iranian woman was referred to our en...
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Acromegaloidism with pituitary microadenoma has not been previously reported. We present a case of a 28-year old male with typical features of acromegaly for 11 years.with a pituitary tumor. He had characteristic acromegaloid facial features, clubbing of hands and feet, enlargement of fingers and toes. The natural history of the disease is reviewed and the differential diagnosis is discussed.
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All patients with pituitary incidentaloma should be investigated for pituitary hyperfunction. The single most important test is measurement of serum prolactin (PRL). Elevated PRL can indicate either direct tumour secretion (levels are typically 800–2,000 mU/l for microprolactinoma, >2,000 mU/l for macroprolactinoma and <600 normally) or ‘disconnection’ of the hypothalamus and normal pituitary g...
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OBJECTIVE Hypersecretion of prolactin (PRL) by lactotroph cells of the anterior pituitary may lead to hyperprolactinemia in physiological or pathological conditions. However, some of the patients may present with another cause of hyperprolactinemia, described by various authors as macroprolactinemia. PATIENTS AND METHODS The clinical, radiological and biochemical assessment of 124 patients we...
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